TY - JOUR AU - Doyle, Mark AU - Weinberg, Nicole AU - Pohost, Gerald M. AU - Merz, C. Noel Bairey AU - Shaw, Leslee J. AU - Sopko, George AU - Fuisz, Anthon AU - Rogers, William J. AU - Walsh, Edward G. AU - Johnson, B. Delia AU - Sharaf, Barry L. AU - Pepine, Carl J. AU - Mankad, Sunil AU - Reis, Steven E. AU - Rayarao, Geetha AU - Vido, Diane A. AU - Bittner, Vera AU - Tauxe, Lindsey AU - Olson, Marian B. AU - Kelsey, Sheryl F. AU - Biederman, Robert WW PY - 2013 TI - Left ventricular energy model predicts adverse events in women with suspected myocardial ischemia: results from the NHLBI-sponsored women’s ischemia syndrome evaluation (WISE) study JF - Cardiovascular Diagnosis and Therapy; Vol 3, No 2 (June 18, 2013): Cardiovascular Diagnosis and Therapy Y2 - 2013 KW - N2 - Objectives: To assess the prognostic value of a left ventricular energy-model in women with suspected myocardial ischemia. Background: The prognostic value of internal energy utilization (IEU) of the left ventricle in women with suspected myocardial ischemia is unknown. Methods: Women [n=227, mean age 59±12 years (range, 31-86 years)], with symptoms of myocardial ischemia, underwent myocardial perfusion imaging (MPI) assessment for regional perfusion defects along with measurement of ventricular volumes separately by gated Single Photon Emission Computed Tomography (SPECT) (n=207) and magnetic resonance imaging (MRI) (n=203). During follow-up (40±17 months), time to first major adverse cardiovascular event (MACE, death, myocardial infarction or hospitalization for congestive heart failure) was analyzed using MRI and gated SPECT variables. Results: Adverse events occurred in 31 (14%). Multivariable Cox models were formed for each modality: IEU and wall thickness by MRI (Chi-squared 34, P UR - https://cdt.amegroups.org/article/view/1879