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Extent of coronary atherosclerosis and arterial remodelling in women: the NHLBI-sponsored Women’s Ischemia Syndrome Evaluation

   
@article{CDT19189,
	author = {Stephen J. Nicholls and E. Murat Tuzcu and Kathy Wolski and B. Delia Johnson and George Sopko and Barry L. Sharaf and Carl J. Pepine and Steven E. Nissen and C. Noel Bairey Merz},
	title = {Extent of coronary atherosclerosis and arterial remodelling in women: the NHLBI-sponsored Women’s Ischemia Syndrome Evaluation},
	journal = {Cardiovascular Diagnosis and Therapy},
	volume = {8},
	number = {4},
	year = {2018},
	keywords = {},
	abstract = {Background: Information regarding the pathogenesis of ischemic heart disease (IHD) in women is limited. Sex-specific responses to atherosclerosis and coronary arterial remodelling in women versus men have been hypothesized, but limited study exists.
Methods: Case-matched study of 174 women with suspected ischemia referred for coronary angiography: 87 with non-obstructive coronary artery disease (CAD) (no luminal diameter stenosis >20% in any coronary artery) and 87 age and ethnicity matched women with obstructive CAD. Groups were compared with regard to atheroma burden and coronary arterial remodelling assessed by coronary artery intravascular ultrasound (IVUS).
Results: IVUS revealed more extensive atheroma with obstructive CAD vs. those without obstructive CAD, with greater percent atheroma volume (PAV) (36.1%±9.8% vs. 25.4%±9.1%, P},
	issn = {2223-3660},	url = {https://cdt.amegroups.org/article/view/19189}
}