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Association between serum adropin level and coronary artery disease: a systematic review and meta-analysis

  
@article{CDT21233,
	author = {Jiankang Zheng and Mao Liu and Ling Chen and Feng Yin and Xiao Zhu and Junqi Gou and Wei Zeng and Zhan Lv},
	title = {Association between serum adropin level and coronary artery disease: a systematic review and meta-analysis},
	journal = {Cardiovascular Diagnosis and Therapy},
	volume = {9},
	number = {1},
	year = {2018},
	keywords = {},
	abstract = {Background: Recent studies have found that adropin is associated with coronary artery disease (CAD). This meta-analysis sought to assess the relationship between serum adropin level and CAD. 
Methods: Online databases including the Cochrane Library, PubMed, EMbase, Ovid, CBM, CNKI, VIP and WanFang Data were electronically searched for the clinical study concerning the relationship between serum adropin levels and CAD, including acute myocardial infarction (AMI), unstable angina pectoris (UAP), and stable angina pectoris (SAP). Two reviewers independently screened literature, extracted data and assessed methodological quality of included studies. Standard mean difference (SMD) with its 95% confidence interval (CI) was used as the effect size in this study. Then meta-analysis was performed using RevMan 5.2 software.
Results: A total of seven articles involved 945 participants were included. The results indicated that serum adropin level in CAD group was lower than healthy control group (SMD =−2.44, P=0.0008). In the subgroup analysis, the levels of serum adropin in AMI group (SMD =−2.96, P},
	issn = {2223-3660},	url = {https://cdt.amegroups.org/article/view/21233}
}