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Two-dimensional speckle tracking of the abdominal aorta: a novel approach to evaluate arterial stiffness in patients with Turner syndrome

   
@article{CDT24585,
	author = {Felix Sebastian Oberhoffer and Hashim Abdul-Khaliq and Anna-Maria Jung and Tilman R. Rohrer and Mohamed Abd El Rahman},
	title = {Two-dimensional speckle tracking of the abdominal aorta: a novel approach to evaluate arterial stiffness in patients with Turner syndrome},
	journal = {Cardiovascular Diagnosis and Therapy},
	volume = {9},
	number = {Suppl 2},
	year = {2019},
	keywords = {},
	abstract = {Background: Turner syndrome (TS) is an X-chromosomal disease affecting one in 2,500–3,000 female newborns. Girls and women with TS show multiple cardiovascular risk factors that all have an impact on arteriosclerosis and thus arterial stiffness. An accurate and non-invasive screening of arterial stiffness is essential to improve the overall outcome in these patients. 
Methods: Thirty-five TS patients and 19 healthy, age-matched controls were prospectively recruited for this study. Arterial stiffness was measured at the abdominal aorta in subxiphoid view using two-dimensional speckle tracking (2DST). Acquisition was performed at a frame rate of 60–90 fps. Mean peak circumferential strain (AAO-S, %) was measured offline for respective layers (inner layer = AAO-SENDO, %; middle layer = AAO-SMESO, %; outer layer = AAO-SEPI, %). 
Results: Compared with the control group, patients with TS showed significantly lower peak circumferential strain values in each layer [AAO-SENDO (mean ± SD): 10.98%±4.73% vs. 15.32%±4.78%, P=0.002; AAO-SMESO (mean ± SD): 6.36%±2.22% vs. 9.18%±2.83%, P},
	issn = {2223-3660},	url = {https://cdt.amegroups.org/article/view/24585}
}