@article{CDT28317,
author = {Ning Li and Lei Ren and Jia Hui Wang and Ya Ru Yan and Ying Ni Lin and Qing Yun Li},
title = {Relationship between monocyte to HDL cholesterol ratio and concomitant cardiovascular disease in Chinese Han patients with obstructive sleep apnea},
journal = {Cardiovascular Diagnosis and Therapy},
volume = {9},
number = {4},
year = {2019},
keywords = {},
abstract = {Background: Obstructive sleep apnea (OSA) is an independent risk factor for cardiovascular disease (CVD), which is attributed to chronic intermittent hypoxia (CIH) induced inflammation. As a new inflammatory biomarker of CVD, monocyte to high-density lipoprotein cholesterol ratio (MHR) has received little attention in OSA studies to date. Therefore, we aimed to investigate the correlation between MHR and concomitant CVD in Chinese Han patients with OSA.
Methods: A total of 657 Chinese Han subjects (169 controls, 145 mild, 94 moderate, and 249 severe OSA) of both genders were enrolled in this cross-sectional study, with an average BMI of 32.35±6.56 kg/m2. The relationship between MHR and concomitant CVD in OSA patients was analyzed.
Results: The level of MHR was correlated positively with apnea-hypopnea index (AHI), while negatively with lowest SpO2 (P},
issn = {2223-3660}, url = {https://cdt.amegroups.org/article/view/28317}
}