%0 Journal Article
%T Accuracy of 3-dimensional and 2-dimensional quantitative coronary angiography for predicting physiological significance of coronary stenosis: a FAVOR II substudy
%A Ding, Daixin
%A Yang, Junqing
%A Westra, Jelmer
%A Chen, Yundai
%A Chang, Yunxiao
%A Sejr-Hansen, Martin
%A Zhang, Su
%A Christiansen, Evald H.
%A Holm, Niels R.
%A Xu, Bo
%A Tu, Shengxian
%J Cardiovascular Diagnosis and Therapy
%D 2019
%B 2019
%9 
%! Accuracy of 3-dimensional and 2-dimensional quantitative coronary angiography for predicting physiological significance of coronary stenosis: a FAVOR II substudy
%K 
%X Background: Three-dimensional quantitative coronary angiography (3D-QCA) enables reconstruction of a coronary artery in 3D from two angiographic image projections. This study compared the diagnostic accuracy of 3D-QCA vs. 2-dimensional (2D) QCA in predicting physiologically significant coronary stenosis, using fractional flow reserve (FFR) as the reference standard.  Methods: All interrogated vessels in the FAVOR II China study and the FAVOR II Europe-Japan study were assessed by 2D-QCA and 3D-QCA according to standard operating procedures in core laboratories. QCA analysts were blinded to the corresponding FFR values.   Results: A total of 645 vessels from 576 patients with 3D-QCA, 2D-QCA, and FFR were analyzed. Using the conventional cut-off value of 50% for percent diameter stenosis (DS%), 3D-QCA was more accurate in predicting FFR ≤0.80 than 2D-QCA [accuracy 74.0% (95% CI: 69.9–77.7%) vs. 64.9% (95% CI: 61.3–68.7%), difference: 9.1%, P
%U https://cdt.amegroups.org/article/view/30157
%V 9
%N 5
%P 481-491
%@ 2223-3660