@article{CDT5191,
author = {Yu Kataoka and Rishi Puri and Muhammad Hammadah and Bhanu Duggal and Kiyoko Uno and Samir R. Kapadia and E. Murat Tuzcu and Steven E. Nissen and Stephen J. Nicholls},
title = {Spotty calcification and plaque vulnerability in vivo: frequency-domain optical coherence tomography analysis},
journal = {Cardiovascular Diagnosis and Therapy},
volume = {4},
number = {6},
year = {2014},
keywords = {},
abstract = {Background: Spotty calcification is a morphological characteristic of a vulnerable plaque phenotype. While this calcium pattern is considered an active process, promoted by inflammation, it is unknown whether spotty calcification associates with development of microstructures observed in vulnerable plaques. As frequencydomain optical coherence tomography (FD-OCT) enables visualization of microstructures associated with plaque vulnerability, we investigated the association between spotty calcification and plaque microstructures by using FD-OCT.
Methods: A total of 300 patients with stable coronary artery disease (CAD), having clinical indication for percutaneous coronary intervention (PCI), were analyzed. Totally 280 non-culprit lipid plaques within the target vessel requiring PCI were evaluated by FD-OCT. Spotty calcification was defined as a presence of lesion },
issn = {2223-3660}, url = {https://cdt.amegroups.org/article/view/5191}
}