The range of articles featured in this focused issue—“mechanism-based therapeutic strategies in type 2 diabetes”—provides key insights on emerging aspects related to the pathogenesis of cardiac and vascular disease as well as CV risk factors in patients with T2D. Collectively, evidence discussed here support a wide translational vision linking disease mechanism to therapeutic approaches. The opening editorial by the guest editors—Drs. Paneni and Costantino—strengthens the importance of translational research in diabetes. The authors focus here on the emerging role of “omics” technologies in the analysis and interpretation of diabetes-related biological signals and their putative link with CV phenotypes.
Guest Editor: Francesco Paneni, MD, PhD, FESC (Karolinska University Hospital, Stockholm, Sweden)
Guest Editor: Sarah Costantino, PhD (Karolinska University Hospital, Stockholm, Sweden)