This series on “Right Ventricular Dysfunction” is edited by:
- Martin Koestenberger, Division of Pediatric Cardiology, Department of Pediatrics, Medical University Graz, Graz, Austria; European Pediatric Pulmonary Vascular Disease Network, Berlin, Germany;
- Harm-Jan Bogaard, Pulmonary Medicine, Amsterdam Cardiovascular Sciences, Amsterdam UMC, location VUmc, Amsterdam, The Netherlands; and
- Georg Hansmann, European Pediatric Pulmonary Vascular Disease Network, Berlin, Germany; Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Hannover, Germany.
In the last decades, substantial progress has been made in the diagnosis and treatment of right ventricular dysfunction in pediatric and adult patients. The pathobiology of right ventricular dysfunction, however, is heterogenous and broad, and, thus, there are many obstacles and areas of uncertainties to unpack. In this special issue, internationally renowned experts from multiple specialties comprehensively discuss impactful discoveries and innovations in the fascinating field of RV dysfunction that have emerged in the last years, both in adult and the pediatric disciplines.
Getting to the bottom of right heart failure
Molecular mechanisms of right ventricular dysfunction in pulmonary arterial hypertension: focus on the coronary vasculature, sex hormones, and glucose/lipid metabolism
Left ventricular dysfunction in heart failure with preserved ejection fraction—molecular mechanisms and impact on right ventricular function
Animal models of right heart failure
Mechanics of right ventricular dysfunction in pulmonary arterial hypertension and heart failure with preserved ejection fraction
Update on noninvasive imaging of right ventricle dysfunction in pulmonary hypertension
Diagnosis and treatment of right ventricular dysfunction in congenital heart disease
Right ventricular dysfunction and long-term risk of death
Treatment of right ventricular dysfunction and heart failure in pulmonary arterial hypertension
Safety and efficacy of the endothelin receptor antagonist macitentan in pediatric pulmonary hypertension
Mineralocorticoid receptor blockade improves pulmonary hypertension and right ventricular function in bronchopulmonary dysplasia: a case report
Prenatal duct closure leading to severe pulmonary hypertension in a preterm neonate—a case report
Interventional creation of an endogenous reverse Potts shunt in an infant with pulmonary hypertension and genetic surfactant disorder—a case report
Cardiac multi-scale investigation of the right and left ventricle ex vivo: a review
Cardiac catheterization in pulmonary hypertension: doing it right, with a catheter on the left
Peri-operative right ventricular dysfunction—the anesthesiologist’s view
Emerging therapies for right ventricular dysfunction and failure
Disclosure:
The focused issue “Right Ventricular Dysfunction” was commissioned by the editorial office, Cardiovascular Diagnosis and Therapy without any sponsorship or funding. Martin Koestenberger, Harm Jan Bogaard and Georg Hansmann served as the unpaid Guest Editors for the focused issue.