Vol 10, No 4 (August 20, 2020): Cardiovascular Diagnosis and Therapy

Original Article

MicroRNA-221 promotes proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs) by targeting tissue inhibitor of metalloproteinases-3 (TIMP3)
Yan Yan, Ying Xu, Gehui Ni, Siqi Wang, Xinli Li, Juan Gao, Haifeng Zhang
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:646-657
.
Inhibition of ERK or Akt ameliorates intimal hyperplasia via up-regulation of Cx37 and down-regulation of Cx43 in balloon injury rat model
Lemen Pan, Haizhen Ni, Wenxu Jin, Xiang Su
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:658-666
.
Incidence of myocardial injury in coronavirus disease 2019 (COVID-19): a pooled analysis of 7,679 patients from 53 studies
Zhi-Chun Gu, Chi Zhang, Ling-Cong Kong, Long Shen, Zheng Li, Heng Ge, Hou-Wen Lin, Jun Pu
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:667-677
.
Analysis of influencing factors related to elevated serum troponin I level for COVID-19 patients in Yichang, China
Zhi-Xing Fan, Jun Yang, Jing Zhang, Chao He, Hui Wu, Chao-Jun Yang, Tao Zheng, Cong Ma, Zu-Jin Xiang, Yu-Hong Zhai, Jing Jiang, Shao-Qin Qiu, Jian Yang
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:678-686
.
MicroRNA-374 is a potential diagnostic biomarker for atherosclerosis and regulates the proliferation and migration of vascular smooth muscle cells
Weihong Wang, Fenghua Ma, Hongyan Zhang
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:687-694
.
Exogenous endothelial progenitor cells reached the deficient region of acute cerebral ischemia rats to improve functional recovery via Bcl-2
Yan Hong, Qing Yu, Zhaohong Kong, Meiyao Wang, Renwei Zhang, Yan Li, Yumin Liu
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:695-704
.
Diminished response to statins predicts the occurrence of heart failure after acute myocardial infarction
Kosuke Tsuda, Yu Kataoka, Soshiro Ogata, Kunihiro Nishimura, Ryo Nishikawa, Takahito Doi, Takahiro Nakashima, Hayato Hosoda, Satoshi Honda, Shoji Kawakami, Masashi Fujino, Kazuhiro Nakao, Shuichi Yoneda, Kensaku Nishihira, Fumiyuki Otsuka, Yoshio Tahara, Yasuhide Asaumi, Masaaki Hoshiga, Teruo Noguchi, Satoshi Yasuda
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:705-716
.
Prevalence and risk factors of left atrial thrombus in patients with atrial fibrillation and lower class (IIa) recommendation to anticoagulants
Beata Uziębło-Życzkowska, Paweł Krzesiński, Agnieszka Jurek, Monika Budnik, Iwona Gorczyca, Agnieszka Kapłon-Cieślicka, Marek Kiliszek, Agnieszka Wójcik, Monika Gawałko, Olga Jelonek, Anna Michalska, Katarzyna Starzyk, Piotr Scisło, Janusz Kochanowski, Krzysztof J. Filipiak, Beata Wożakowska-Kapłon, Grzegorz Opolski, Grzegorz Gielerak
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:717-724
.
Performance of cardiovascular magnetic resonance strain in patients with acute myocarditis
Xiaorong Chen, Hongjie Hu, Jiangfeng Pan, Jiner Shu, Yi Hu, Risheng Yu
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:725-737
.
Hypermethylation of miR-181b in monocytes is associated with coronary artery disease and promotes M1 polarized phenotype via PIAS1-KLF4 axis
Zhonghua Wang, Chunlei Li, Xinyong Sun, Zhuqin Li, Jia Li, Lanfeng Wang, Yanming Sun
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:738-751
.
Curcumin suppresses doxorubicin-induced cardiomyocyte pyroptosis via a PI3K/Akt/mTOR-dependent manner
Wei Yu, Xing Qin, Yuchen Zhang, Peng Qiu, Linge Wang, Wenliang Zha, Jun Ren
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:752-769
.
Nomogram developed with selenoprotein S (SelS) genetic variation and clinical characteristics predicting risk of coronary artery disease in a Chinese population
Ding-Yu Wang, Ting-Ting Wu, Ying-Ying Zheng, Yi-Tong Ma, Xiang Xie
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:770-777
.
Ephrin B2 mediates high glucose induced endothelial-to-mesenchymal transition in human aortic endothelial cells
Cheng Yuan, Lihua Ni, Changjiang Zhang, Hao Xia, Xiaoyan Wu
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:778-785
.
Are dilated ascending aortas of Chinese patients more likely to dissect?
Wenjian Jiang, Jihong Liu, Lu Dai, Yang Liu, Zining Wu, Hongjia Zhang
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:786-795
.
Study on the mechanism of anti-MIRI action of total flavones of Fructus Chorspondiatis by PET/CT imaging
Guo-Jian Zhang, Li-Hong Wei, Hai-Wen Lu, Yun-Feng Xiao, Wen-Rui Wang, Yu-Lin He, Xue-Mei Wang, Jia-He Tian
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:796-810
.
Downregulation of long noncoding RNA SNHG6 rescued propofol-induced cytotoxicity in human induced pluripotent stem cell-derived cardiomyocytes
Zhongguo Ren, Rong Hu
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:811-819
.
Machine learning-based CT fractional flow reserve assessment in acute chest pain: first experience
Matthias Eberhard, Tin Nadarevic, Andrej Cousin, Jochen von Spiczak, Ricarda Hinzpeter, Andre Euler, Fabian Morsbach, Robert Manka, Dagmar I. Keller, Hatem Alkadhi
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:820-830
.
Effectiveness of magnetocardiography to identify patients in need of coronary artery revascularization: a cross-sectional study
Xiao Huang, Ning Hua, Fakuan Tang, Shulin Zhang
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:831-840
.
Early clinical outcomes of thoracoscopic mitral valvuloplasty: a clinical experience of 100 consecutive cases
Huimin Cui, Lin Zhang, Shixiong Wei, Lianggang Li, Tong Ren, Yao Wang, Shengli Jiang
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:841-848
.
MiR-181c protects cardiomyocyte injury by preventing cell apoptosis through PI3K/Akt signaling pathway
Xiaoli Li, Jiuchang Zhong, Zhen Zeng, Hongjiang Wang, Jing Li, Xiaoyan Liu, Xinchun Yang
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:849-858
.
A comparison of artificial intelligence-based algorithms for the identification of patients with depressed right ventricular function from 2-dimentional echocardiography parameters and clinical features
Ali Ahmad, Zahi Ibrahim, Georges Sakr, Abdallah El-Bizri, Lara Masri, Imad H. Elhajj, Nehme El-Hachem, Hussain Isma’eel
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:859-868
.

Review Article

Implications of gut microbiome on coronary artery disease
Jing Xu, Yuejin Yang
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:869-880
.
Research advances in myocardial injury caused by COVID-19
Jianjun Chen, Yingfeng He, Liangliang Zhou, Genhua Mu, Youlin Ji
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:881-887
.

Case Report

Mediastinal liposarcoma masquerading as penetrating aortic ulcer in the descending aorta: a case report
Lei Wang, Junyuan Lv, Ruoran Lin, Xuan Li, Xiaoming Cheng, Shijie Xin
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:888-891
.
Pulmonary vascular endothelial injury and acute pulmonary hypertension caused by COVID-19: the fundamental cause of refractory hypoxemia?
Xinxin Wang, Yunliang Tu, Bin Huang, Yinfeng Li, Yanyan Li, Sheng Zhang, Yingxin Lin, Lei Huang, Weixing Zhang, Hua Luo
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:892-897
.
COVID-19 pandemic and stent thrombosis in a post percutaneous coronary intervention patient-a case report highlighting the selection of P2Y12 inhibitor
Rahul Choudhary, Atul Kaushik, Jai Bharat Sharma
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:898-901
.
Cardiogenic shock in an 8-year-old child secondary to anomalous coronary origin and course: a case report on the value of coronary computed tomography angiography and cardiac magnetic resonance
Xiaorong Chen, Jiangfeng Pan, Jiner Shu, Yi Hu, Risheng Yu
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:902-907
.

Brief Report

Will ISCHEMIA change our daily practice?
David Meier, Thabo Mahendiran, Stephane Fournier
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:908-911
.

Letter to the Editor

The potential for missed work days due to possible COVID-19 exposure at large scientific meetings
Anirudh Kumar, Divyang R. Patel, Milind Y. Desai
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:912-914
.

Editorial on Advanced Imaging in The Diagnosis of Cardiovascular Diseases1

Advanced imaging in the diagnosis of cardiovascular diseases: the “ongoing” future
Luca Saba
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:915-918
.

Original Article on Advanced Imaging in The Diagnosis of Cardiovascular Diseases1

Cardiovascular/stroke risk predictive calculators: a comparison between statistical and machine learning models
Ankush Jamthikar, Deep Gupta, Luca Saba, Narendra N. Khanna, Tadashi Araki, Klaudija Viskovic, Sophie Mavrogeni, John R. Laird, Gyan Pareek, Martin Miner, Petros P. Sfikakis, Athanasios Protogerou, Vijay Viswanathan, Aditya Sharma, Andrew Nicolaides, George D. Kitas, Jasjit S. Suri
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:919-938
.
Ultrasound-based stroke/cardiovascular risk stratification using Framingham Risk Score and ASCVD Risk Score based on “Integrated Vascular Age” instead of “Chronological Age”: a multi-ethnic study of Asian Indian, Caucasian, and Japanese cohorts
Ankush Jamthikar, Deep Gupta, Elisa Cuadrado-Godia, Anudeep Puvvula, Narendra N. Khanna, Luca Saba, Klaudija Viskovic, Sophie Mavrogeni, Monika Turk, John R. Laird, Gyan Pareek, Martin Miner, Petros P. Sfikakis, Athanasios Protogerou, George D. Kitas, Chithra Shankar, Andrew Nicolaides, Vijay Viswanathan, Aditya Sharma, Jasjit S. Suri
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:939-954
.

Review Article on Advanced Imaging in The Diagnosis of Cardiovascular Diseases1

Uses of ultrasound in stroke prevention
J. David Spence
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:955-964
.
Contrast imaging ultrasound for the detection and characterization of carotid vulnerable plaque
Vasileios Rafailidis, Xin Li, Paul S. Sidhu, Sasan Partovi, Daniel Staub
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:965-981
.
Vessel wall MR imaging of intracranial atherosclerosis
Jae W. Song, Bruce A. Wasserman
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:982-993
.
Imaging of intracranial atherosclerotic plaques using 3.0 T and 7.0 T magnetic resonance imaging—current trends and future perspectives
Fang Wu, Huan Yu, Qi Yang
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:994-1004
.
Carotid plaque imaging profiling in subjects with risk factors (diabetes and hypertension)
Michele Porcu, Lorenzo Mannelli, Marta Melis, Jasjit S. Suri, Clara Gerosa, Giulia Cerrone, Giovanni Defazio, Gavino Faa, Luca Saba
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:1005-1018
.
MR imaging of vulnerable carotid plaque
Michael E. Porambo, J. Kevin DeMarco
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:1019-1031
.
Plaque imaging volume analysis: technique and application
Alessandro Murgia, Antonella Balestrieri, Marco Francone, Pierleone Lucatelli, Elisa Scapin, Andrew Buckler, Giulio Micheletti, Gavino Faa, Maurizio Conti, Jasjit S. Suri, Giuseppe Guglielmi, Alessandro Carriero, Luca Saba
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:1032-1047
.
Carotid plaque imaging and the risk of atherosclerotic cardiovascular disease
Guangming Zhu, Jason Hom, Ying Li, Bin Jiang, Fatima Rodriguez, Dominik Fleischmann, David Saloner, Michele Porcu, Yanrong Zhang, Luca Saba, Max Wintermark
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:1048-1067
.
4D flow imaging of the thoracic aorta: is there an added clinical value?
Federica Catapano, Giacomo Pambianchi, Giulia Cundari, João Rebelo, Francesco Cilia, Iacopo Carbone, Carlo Catalano, Marco Francone, Nicola Galea
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:1068-1089
.
Dual-energy CT and coronary imaging
Fernando Uliana Kay
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:1090-1107
.
Vessel wall MR imaging for the detection of intracranial inflammatory vasculopathies
Myriam Edjlali, Ye Qiao, Gregoire Boulouis, Nicolas Menjot, Luca Saba, Bruce Alan Wasserman, Javier M. Romero
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:1108-1119
.
PET/MRI of atherosclerosis
Mueez Aizaz, Rik P. M. Moonen, Jochem A. J. van der Pol, Claudia Prieto, René M. Botnar, M. Eline Kooi
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:1120-1139
.
Heart applications of 4D flow
Giuseppe Corrias, Daniele Cocco, Jasjit S. Suri, Luigi Meloni, Filippo Cademartiri, Luca Saba
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:1140-1149
.
Insight from imaging on plaque vulnerability: similarities and differences between coronary and carotid arteries—implications for systemic therapies
Filippo Cademartiri, Antonella Balestrieri, Riccardo Cau, Bruna Punzo, Carlo Cavaliere, Erica Maffei, Luca Saba
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:1150-1162
.

Arts and Medicine2

Deep time and the unsettling bite of impermanence
Jonathan Latiano
Cardiovascular Diagnosis and Therapy  
2020;
10
(4)
:1163-1166
.

Disclosure:

1. The series “Advanced Imaging in The Diagnosis of Cardiovascular Diseases” was commissioned by the editorial office, Cardiovascular Diagnosis and Therapy without any sponsorship or funding. Luca Saba served as the unpaid Guest Editor for the series.

2. The series “Arts and Medicine” was commissioned by the editorial office, Cardiovascular Diagnosis and Therapy without any sponsorship or funding.